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    What's New
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  • May 15 2019, Jul 19 2014, Jan 16 2014, Apr 9 2013
    • Minor modification
  • Oct 25 2012
    • Minor bug fixed
  • Aug 23 2012
    • ABI format file (with ".ab1" extension) is now acceptable for bisuflite sequece file
  • May 23 2012
    • Exclude identical bisulfite sequences option is added
  • Jan 13 2012
    • Minor bug fixed
  • Sep 14 2011
    • Minor bug fixed
  • Jan 29 2011
    • Strict CpG site check option for repeptive sequence analysis is added
  • Nov 12 2010
    • Performance of Fisher's exact test is improved
  • Oct 22 2010
    • Character-Based User Interface version is now available at the download section
  • Jun 14 2010
    • Minor bug fixed
  • Feb 2 2010
    • Modification of font size for long sequence name
  • Jan 28, Jan 30 and Feb 4, 2009
    • Bugs of the coversion options ("G => A conversion" and "Both") are fixed
      • Some of the analysis results were displayed leftside righ when analyzed with "G => A conversion" or "Both" option.
  • Jan 8, 2009   More detail
    • QUMA now support "Save and Restore" function
    • Multiple-alignment format display now available
    • Now support circle graph style methylation pattern figure
    • Now support CpG number display function at the methylation pattern figures
    • Now display S.D. (standard deviation) and S.E. (standard error) for the CpG methylation status
  • Sep 25, 2008
    • QUMA now support SVG file format for graphics data download. SVG file format is suitable to use for a journal figure.
  • May 16, 2008
  • May 2, 2008
    • More options about CpG positions added to the function of making methylation pattern figure
    • Function of addition/replacement of bisulfite sequences is added to the result page of the methylation status analysis mode
    • Manuscript of QUMA has been accepted by NAR
    • Download files updated
    • "Links" section now available and "Acknowledgements" section was integrated into "Reference" section
  • Apr 21, 2008
    • CpG position number bug of the methylation pattern figure fixed
    • Typos fixed
  • Apr 17, 2008
    • "Download" section now available
      • Program source code of the QUMA now available
      • LiveCD (bootable CD) version of the QUMA now available
    • QUMA User's Manual updated
    • New "Show CpG position" option added to the function of making methylation pattern figure
    • New sorting condition "sequence name" added, "How to use" section updated, some online helps added, site structure changed, some descriptions changed and some minor functions added.
    • Implementation of Mann-Whiteney U-test is changed: now using exact test for small number of sequences (20 and below).
  • Mar 31, 2008
    • The last line truncation bug of the multi-fasta sequence input is fixed.
  • Feb 21, 2008
    • "Terms of Use" section now available
    • Minor bug fixed and "Acknowledgements" section updated
  • Feb 18, 2008
    • Typos fixed and "Acknowledgements" section updated
  • Jan 30, 2008
    • QUMA User's Manual now available
    • Typos fixed, "Acknowledgements" and "Reference" sections updated, and "What's New" column created
  • Updated at Nov 29 and 30, Dec 4, 5, 12, 13 and 14, 2007, Jan 04 and 17 2008
  • Nov 23, 2007
    • The QUMA web server now available

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If you have any questions/comments/requests etc., please feel free to contact  : 
quma@cdb.riken.jp
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QUMA (QUantification tool for Methylation Analysis) top